A lot of people describe themselves as nerds these days who really aren't. They're hipsters. But if you have a hard time differentiating, no one can blame you as there are plenty of similarities. Nevertheless, there are a few hipster tells.
Redditor moson posted this helpful image that clearly outlines the differences between nerds and hipsters. Fun fact: the original photo is of actual, honest-to-god scientist nerds from Poland. Hooray!
CENTER POINT, Alabama -- Although a city ordinance bans pit bulls and other "dangerous dogs" inside city limits, recent incidents have raised concerns about the animals.
Mary Margaret Hampton on Thursday told city council members three pit bulls belonging to a neighbor entered her yard twice since January, killing her Siamese cat and a Chihuahua puppy.
"They tried to attack me," Hampton said. "They tore the gate off the porch and tried to get into my house."
On Wednesday, a Jefferson County deputy sheriff shot a pit bull that lunged at him in Center Point. The dog was one of three that chased a woman into her house, said Chief Deputy Randy Christian. Another of the dogs was captured.
After Hampton's cat was killed, the neighbor's dogs were quarantined and the owners were told they had a week to get rid of the animals or a citation would be issued, a deputy told city officials Thursday night. Despite the warning, the animals were later brought back.
Mayor Tom Henderson said that happens all too often.
"Write them a citation right then. They're illegal period," Henderson said.
Other city officials agreed.
"You have to issue the citation to get the court process started," said Council President Roger Barlow.
Council member Linda Kennemur, chairwoman of the public safety committee, said the issue would be a good topic of discussion for the next community watch meeting, being held Tuesday at 7 p.m. at City Hall.
The city Council in 2008 passed what it calls a "dangerous dog ordinance" that outlaws the keeping of pit bulls and any dogs "with a propensity, tendency or disposition to attack unprovoked" or any dog that is aggressive by nature.
OUYA may have nabbed the spotlight in the Android-based, Kickstarter-supported console wars, but the diminutive GameStick's got some heat behind it, too. The device's makers are putting on a bit of a show at this year's GDC, announcing a slew of news around the forthcoming product. At the top of the list are a number of backers, including, most prominently, the similarly-named GameStop, which clearly sees a viable future in such products, as the world continues to move away from brick-and-mortar outlets. Shadowgun and Smash Cops were also revealed as pre-installed titles for the console, "ensuring GameStick users have free, quality content ready to go out of the box."
The Tulsa Health Department is warning 7,000 patients of a local dentist's office that they could have contracted HIV, hepatitis B or hepatitis C from poor sterilization practices.
Dr. Wayne Harrington, an oral surgeon with a practice in Tulsa, Okla., is being investigated by the state dental board, the state bureau of narcotics and the federal Drug Enforcement Agency because one of his patients recently tested positive for hepatitis C and HIV without known risk factors other than receiving dental treatment.
Upon hearing of the infected patient, the Oklahoma Board of Dentistry conducted a surprise inspection of Harrington's practice on March 18, allegedly finding numerous problems, including regular use of a rusty set of instruments on patients with known infections, and the practice of pouring bleach on wounds until they "turned white."
Calls to Harrington's office were directed to an operator, who told ABC News the clinic no longer took voicemails. The operator said patients were being referred to another clinic, but did not disclose the clinic's name.
Susan Rogers, executive director of Oklahoma's Board of Dentistry, called the incident a "perfect storm." On top of his many violations in sanitary practice, the dentist was a Medicaid provider, which means he had a high proportion of patients with HIV or hepatitis, she said.
Harrington and his staff told investigators that he treated a "high population of known infectious disease carrier patients," according to a complaint filed by the Oklahoma Board of Dentistry.
He allegedly allowed unlicensed dental assistants to administer medication, according to the complaint. These assistants were left to decide which medications to administer, and how much was appropriate.
Drug cabinets were unlocked and unsupervised during the day, and Harrington did not keep an inventory log of drugs, some of which were controlled substances. One drug vial expired in 1993.
"During the inspections, Dr. Harrington referred to his staff regarding all sterilization and drug procedures in his office," the complaint read. "He advised, 'They take care of that. I don't.'"
Harrington allegedly re-used needles, contaminating drugs with potentially harmful bacteria and trace amounts of other drugs, according to the complaint. Although patient-specific drug records indicated that they were using morphine in 2012, no morphine had been ordered since 2009.
The instruments for infected patients was given an extra dip in bleach in addition to normal cleaning methods, but they had red-brown rust spots, indicating that they were "porous and cannot be properly sterilized," according to the complaint.
The Tulsa Health Department said Harrington's patients will receive letters by mail notifying them of the risk and steps to obtain free-of-charge testing.
While 7,000 patients may have been exposed, Joseph Perz, an epidemiologist with the U.S. Centers for Disease Control and Prevention, said it's "extremely rare" to see dental transmission of HIV and hepatitis B or C. In July 2012, 8,000 Coloradans were notified that their dentist had reused needles, potentially exposing them to the blood-borne viruses. But not a single case was identified, according to the CDC.
Dental transmission is not impossible, however. Perz cited a dental fair three years ago in which hepatitis B was transmitted between patients.
In July 2012, more than 1,800 veterans who received dental care at a St. Louis VA Medical Center were warned that improper cleaning of dental tools may have exposed them to HIV and hepatitis.
The Tulsa Health Department has set up a hotline at (918) 595-4500 for people with questions.
ABC News' Dr. Richard Besser and Katie Moisse contributed to this story.
Mar. 27, 2013 ? The Universe is an old neighbourhood -- roughly 13.8 billion years old. Our galaxy, the Milky Way, is also ancient -- some of its stars are more than 13 billion years old. Nevertheless, there is still a lot of action: new objects form and others are destroyed. In this image, you can see some of the newcomers, the young stars forming the cluster NGC 2547.
But, how young are these cosmic youngsters really? Although their exact ages remain uncertain, astronomers estimate that NGC 2547's stars range from 20 to 35 million years old. That doesn't sound all that young, after all. However, our Sun is 4600 million years old and has not yet reached middle age. That means that if you imagine that the Sun as a 40 year-old person, the bright stars in the picture are three-month-old babies.
Most stars do not form in isolation, but in rich clusters with sizes ranging from several tens to several thousands of stars. While NGC 2547 contains many hot stars that glow bright blue, a telltale sign of their youth, you can also find one or two yellow or red stars which have already evolved to become red giants. Open star clusters like this usually only have comparatively short lives, of the order of several hundred million years, before they disintegrate as their component stars drift apart.
Clusters are key objects for astronomers studying how stars evolve through their lives. The members of a cluster were all born from the same material at about the same time, making it easier to determine the effects of other stellar properties.
The star cluster NGC 2547 lies in the southern constellation of Vela (The Sail), about 1500 light-years from Earth, and is bright enough to be easily seen using binoculars. It was discovered in 1751 by the French astronomer Nicolas-Louis de Lacaille during an astronomical expedition to the Cape of Good Hope in South Africa, using a tiny telescope of less than two centimetres aperture.
Between the bright stars in this picture you can see plenty of other objects, especially when zooming in. Many are fainter or more distant stars in the Milky Way, but some, appearing as fuzzy extended objects, are galaxies, located millions of light-years beyond the stars in the field of view.
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Penn researchers show stem cell fate depends on 'grip' Public release date: 28-Mar-2013 [ | E-mail | Share ]
Contact: Evan Lerner elerner@upenn.edu 215-573-6604 University of Pennsylvania
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.
The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen.
Their study was published in the journal Nature Materials.
Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been done in three dimensions. Three-dimensional environments, or matrices, for stems cells have mostly been treated as simple scaffolding, rather than as a signal that influences the cells' development.
Burdick and his colleagues were interested in how these three-dimensional matrices impact mechanotransduction, which is how the cell takes information about its physical environment and translates that to chemical signaling.
"We're trying to understand how material signals can dictate stem cell response," Burdick said. "Rather than considering the material as an inert structure, it's really guiding stem cell fate and differentiation what kind of cells they will turn into."
The mesenchymal stem cells the researchers studied are found in bone marrow and can develop into several cell types: osteoblasts, which are found in bone; chondrocytes, which are found in cartilage; and adipocytes, which are found in fat.
The researchers cultured them in water-swollen polymer networks known as hydrogels, which share some similarities with the environments stem cells naturally grow in. These materials are generally soft and flexible contact lenses, for example, are a type of hydrogel but can vary in density and stiffness depending on the type and quantity of the bonds between the polymers. In this case, the researchers used covalently cross-linked gels, which contain irreversible chemical bonds.
When seeded on top of two-dimensional covalently cross-linked gels, mesenchymal stem cells spread and pulled on the material differently depending on how stiff it was. Critically, the mechanics guide cell fate, or the type of cells they differentiate it into. A softer environment would produce more fat-like cells and a stiffer environment, where the cells can pull on the gel harder, would produce more bone-like cells.
However, when the researchers put mesenchymal stem cells inside three-dimensional hydrogels of varying stiffness, they didn't see these kinds of changes.
"In most covalently cross-linked gels, the cells can't spread into the matrix because they can't degrade the bonds they all become fat cells," Burdick said. "That tells us that in 3D covalent gels the cells don't translate the mechanical information the same way they do in a 2D system."
To test this, the researchers changed the chemistry of their hydrogels so that the polymer chains were connected by a peptide that the cells could naturally degrade. They hypothesized that, as the cells spread, they would be able to get a better grip on their surrounding environment and thus be more likely to turn into bone-like cells.
In order to determine how well the cells were pulling on their environment, the researchers used a technique developed by Chen's lab called 3D traction force microscopy. This technique involves seeding the gel with microscopic beads, then tracking their location before and after a cell is removed.
"Because the gel is elastic and will relax back into its original position when you remove the cells," Chen said, "you can quantify how much the cells are pulling on the gel based on how much and which way it springs back after the cell is removed."
The results showed that the stem cells' differentiation into bone-like cells was aided by their ability to better anchor themselves into the growth environment.
"With our original experiment, we observed that the cells essentially didn't pull on the gel. They adhered to it and were viable, but we did not see bead displacement. They couldn't get a grip," Burdick said. "When we put the cells into a gel where they could degrade the bonds, we saw them spread into the matrix and deform it, displacing the beads."
As an additional test, the researchers synthesized another hydrogel. This one had the same covalent bonds that the stem cells could naturally degrade and spread through but also another type of bond that could form when exposed to light. They let the stem cells spread as before, but at the point the cells would begin to differentiate about a week after they were first encapsulated the researchers further "set" the gel by exposing it to light, forming new bonds the cells couldn't degrade.
"When we introduced these cross-links so they could no longer degrade the matrix, we saw an increase toward fat-like cells, even after letting them spread," Burdick said. "This further supports the idea that continuous degradation is needed for the cells to sense the material properties of their environment and transduce that into differentiation signals."
Burdick and his colleagues see these results as helping develop a better fundamental understanding of how to engineer tissues using stem cells.
"This is a model system for showing how the microenvironment can influence the fate of the cells," Burdick said.
###
The research was supported by the National Science Foundation, the National Institutes of Health and the David and Lucile Packard Foundation.
Sudhir Khetan is now an assistant professor of bioengineering at Union College.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Penn researchers show stem cell fate depends on 'grip' Public release date: 28-Mar-2013 [ | E-mail | Share ]
Contact: Evan Lerner elerner@upenn.edu 215-573-6604 University of Pennsylvania
The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.
The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen.
Their study was published in the journal Nature Materials.
Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been done in three dimensions. Three-dimensional environments, or matrices, for stems cells have mostly been treated as simple scaffolding, rather than as a signal that influences the cells' development.
Burdick and his colleagues were interested in how these three-dimensional matrices impact mechanotransduction, which is how the cell takes information about its physical environment and translates that to chemical signaling.
"We're trying to understand how material signals can dictate stem cell response," Burdick said. "Rather than considering the material as an inert structure, it's really guiding stem cell fate and differentiation what kind of cells they will turn into."
The mesenchymal stem cells the researchers studied are found in bone marrow and can develop into several cell types: osteoblasts, which are found in bone; chondrocytes, which are found in cartilage; and adipocytes, which are found in fat.
The researchers cultured them in water-swollen polymer networks known as hydrogels, which share some similarities with the environments stem cells naturally grow in. These materials are generally soft and flexible contact lenses, for example, are a type of hydrogel but can vary in density and stiffness depending on the type and quantity of the bonds between the polymers. In this case, the researchers used covalently cross-linked gels, which contain irreversible chemical bonds.
When seeded on top of two-dimensional covalently cross-linked gels, mesenchymal stem cells spread and pulled on the material differently depending on how stiff it was. Critically, the mechanics guide cell fate, or the type of cells they differentiate it into. A softer environment would produce more fat-like cells and a stiffer environment, where the cells can pull on the gel harder, would produce more bone-like cells.
However, when the researchers put mesenchymal stem cells inside three-dimensional hydrogels of varying stiffness, they didn't see these kinds of changes.
"In most covalently cross-linked gels, the cells can't spread into the matrix because they can't degrade the bonds they all become fat cells," Burdick said. "That tells us that in 3D covalent gels the cells don't translate the mechanical information the same way they do in a 2D system."
To test this, the researchers changed the chemistry of their hydrogels so that the polymer chains were connected by a peptide that the cells could naturally degrade. They hypothesized that, as the cells spread, they would be able to get a better grip on their surrounding environment and thus be more likely to turn into bone-like cells.
In order to determine how well the cells were pulling on their environment, the researchers used a technique developed by Chen's lab called 3D traction force microscopy. This technique involves seeding the gel with microscopic beads, then tracking their location before and after a cell is removed.
"Because the gel is elastic and will relax back into its original position when you remove the cells," Chen said, "you can quantify how much the cells are pulling on the gel based on how much and which way it springs back after the cell is removed."
The results showed that the stem cells' differentiation into bone-like cells was aided by their ability to better anchor themselves into the growth environment.
"With our original experiment, we observed that the cells essentially didn't pull on the gel. They adhered to it and were viable, but we did not see bead displacement. They couldn't get a grip," Burdick said. "When we put the cells into a gel where they could degrade the bonds, we saw them spread into the matrix and deform it, displacing the beads."
As an additional test, the researchers synthesized another hydrogel. This one had the same covalent bonds that the stem cells could naturally degrade and spread through but also another type of bond that could form when exposed to light. They let the stem cells spread as before, but at the point the cells would begin to differentiate about a week after they were first encapsulated the researchers further "set" the gel by exposing it to light, forming new bonds the cells couldn't degrade.
"When we introduced these cross-links so they could no longer degrade the matrix, we saw an increase toward fat-like cells, even after letting them spread," Burdick said. "This further supports the idea that continuous degradation is needed for the cells to sense the material properties of their environment and transduce that into differentiation signals."
Burdick and his colleagues see these results as helping develop a better fundamental understanding of how to engineer tissues using stem cells.
"This is a model system for showing how the microenvironment can influence the fate of the cells," Burdick said.
###
The research was supported by the National Science Foundation, the National Institutes of Health and the David and Lucile Packard Foundation.
Sudhir Khetan is now an assistant professor of bioengineering at Union College.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Generally, a character skeleton sheet is here for the purpose of making things simple. That means that you are not restricted to what's on the skeleton. It's built to be customizable, to provide information about your character. The provided sheet is simple yet effective, allowing you to add/remove portions that might or might not pertain to your character.
Code: Select all
[b]Personal Information[/b] [i]Name: Nickname: Callsign: Age: [18-45] Gender: Fireteam: Specialization: [Assault? Team's medic?] Skills: [3 primary skills maximum] [/i] [b]Description:[/b] [b]Bio:[/b] [This form regards to your character's history, skills, ect.] [b]Specialty Weapon:[/b] [This question regards as to if the character prefers a certain weapon.] [b]Sidearms:[/b] [b]Equipment:[/b] [Include everything that range from possible armor (including modifications) to miscellaneous items.] [b]Song / lyrics:[/b] [If you can, please provide a link to the song as well. It helps add to the atmosphere that represents the character. Theme song in other words.]
Dolphin Android-trash Git 3.5-1062 is compiled. Dolphin Android-trash Git is a branch of Dolphin. Dolphin is the first Gamecube emulator able to run commercial games! Dolphin is a Gamecube, Wii and Triforce (the arcade machine based on the Gamecube) emulator which supports many extra features and abilities not present on the original consoles. It has a partial Wii support and plays most Gamecube games.
Dolphin Android-trash Git changelog: * Big commit. Fix running the APK, I had missed a view in the manifest. Clean up the Android EGL context creation to fit more in line with how Dolphin works. This breaks input at the moment as well. Change the memarena from 768MB to 64MB to allow 1GB phones to potentially run it. Rename EGL_X11 back to EGL since this merge brings in some of soreau's changes to more easily allow different platforms like Wayland and Android. Not quite all of the code because some needs to be cleaned up still. * Android mega commit of trash.
Download: Dolphin Android-trash Git 3.5-1062 x86 Download: Dolphin Android-trash Git 3.5-1062 x64 Source: Here
LONDON (AP) ? Stocks around the world fell sharply Monday as investors fretted over a weekend plan to tax depositors in Cypriot banks as part of a bailout of the Mediterranean island nation.
Though Cyprus accounts for only around 0.2 percent of the combined output of the 17 European Union countries that use the euro, the tax on depositors has stoked fears of bank runs in other troubled European economies.
Since the European debt crisis began in late 2009, savers have been spared. The bailout of Cyprus, agreed to early Saturday, foresees a 6.75 percent levy on deposits below ?100,000 ($130,860) rising to 9.9 percent on those above.
"In the medium term the decision taken regarding the loss on bank deposits could have major ramifications for the eurozone if the European debt crisis re-escalates," said Gary Jenkins, managing director of Swordfish Research. "What I find most surprising is that they are prepared to take such a major gamble to save such a small amount of money."
In Europe, the FTSE 100 index of leading British shares was down 0.8 percent at 6,439 while Germany's DAX fell 1.1 percent to 7,954. The CAC-40 in France was 1.3 percent lower at 7,945. Cyprus' stock exchange is closed for a bank holiday.
The euro was taking a pounding too, down 0.7 percent at $1.2954.
People in Cyprus have reacted with fury to the news and the country's new president is apparently working out a new plan to be put to Parliament that will limit the hit on small depositors. Parliament is due to vote on the bailout later. If it backs the levy, then Cyprus would be eligible for a ?10 billion ($13 billion) financial rescue from its partners in the eurozone and the International Monetary Fund.
German finance minister Wolfgang Schaeuble said Sunday that a no vote by Cypriot lawmakers would have huge repercussions in the country.
"Then the Cypriot banks will no longer be solvent, and Cyprus will be in a very difficult situation," said Schaeuble, who insisted that every country involved in Europe's debt crisis is different. In the case of Cyprus, he said bank owners and investors had to participate in the rescue.
"It can't be done any other way if we want to avoid insolvency," he said.
Cyprus' banking sector is about eight times the size of the economy and has been accused of being a hub for money-laundering, particularly from Russia. That's why many European officials wanted to have the banks' depositors involved in the cost of the bailout.
"If European policymakers were looking for a way to undermine the public trust that underpins the foundation of any banking system they could not have done a better job," said Michael Hewson, senior market analyst at CMC Markets.
In Asia, Japan's Nikkei 225 index slid 2.7 percent to 12,220.63, while Hong Kong's Hang Seng dropped 2 percent to 22,082.83.
Wall Street was headed for a retreat at the open too, with Dow futures down 0.5 percent and the broader S&P 500 futures 0.8 percent lower.
Oil prices were under pressure, with the benchmark New York rate 94 cents lower at $92.51 a barrel.
___
Geir Moulson in Berlin contributed to this report.
WASHINGTON (AP) ? Unemployment rates increased in half of U.S. states in January from December, as employers nationwide added the fewest jobs in seven months.
The Labor Department said Monday that unemployment rates rose in 25 states. They fell in only 8 states and were unchanged in 17.
Despite the increase, some long-suffering states showed improvement in January.
Florida's unemployment rate fell below the national level for the first time in five years, further evidence that the state is recovering from a deep housing slump.
And Michigan, which has benefited from the comeback of the auto industry, added 26,500 jobs in January ? the most of any state. Its unemployment rate was unchanged at 8.9 percent.
Nationally, the unemployment rate ticked up in January to 7.9 percent from 7.8 percent in December. Employers added only 119,000 jobs, down from 219,000 in December.
Job gains have since accelerated. Employers added 236,000 jobs in February, and the national unemployment rate fell to a four-year low of 7.7 percent.
Florida has added 127,500 jobs in the past year, the third most of any state. The state has benefited from greater tourism as the U.S. economy has slowly recovered. That has led to more jobs at hotels, restaurants and retail stores.
North Dakota had the lowest unemployment rate among states in January, at 3.3 percent. It has benefited from an oil and gas boom. Nebraska had the second lowest at 3.8 percent, followed by South Dakota at 4.4 percent.
California and Rhode Island reported the highest state unemployment rates in January, both at 9.8 percent.
Nevada had the third highest, at 9.7 percent. Still, that's down from 9.8 percent in December. And the state's unemployment rate has fallen sharply over the past 12 months, down from 12 percent in January 2012. That's the biggest year-over-year drop of any state.
One reason for the rapid decline is many out-of-work people in Nevada have stopped looking for jobs. Nevada's work force fell 1.2 percent in the 12 months through January. The government counts people as unemployed only if they are actively looking for work.
Still, some of those out of work have found jobs. In the past year, the number of jobs in the state has increased 2.5 percent.
Anti-war essays, poems, short stories and literary excerpts
Romain Rolland: Selections on war
====
Romain Rolland From War Literature (1915) Translated by C.K. Ogden
The intellectuals on both sides have been much in evidence since the beginning of the war; they have, indeed, brought so much violence and passion to bear upon it, that it might almost be called their war!
It seems to me, however, that attention has not been sufficiently drawn to the fact that, with a few exceptions, it is only the voice of the older generation that has been heard ? the voice of Academicians, and Professoren, of distinguished members of the press and the universities, of poets of established reputations, and the doyens of literature, art, and science.
***
[T]he one German poet who has written the serenest and loftiest words, and preserved in the midst of this demoniacal war an attitude worthy of Goethe, is Hermann Hesse. He continues to live at Berne, and, sheltered there from the moral contagion, he has deliberately kept aloof from the combat. All will remember his noble article in the Neue Z?rcher Zeitung of November 3rd, ?O Freunde, nicht diese T?ne!? in which he implored the artists and thinkers of Europe ?to save what little peace? might yet be saved, and not to join with their pens in destroying the future of Europe. Since then he has written some beautiful poems, one of which, an Invocation to Peace, is inspired with deep feeling and classical simplicity, and will find its way to many an oppressed heart.
Jeder hat?s gehabt Keiner hat?s gesch?tzt. Jeden hat der s?sse Quell gelabt. O wie klingt der Name Friede jetzt!
Klingt so fern und zag, Klingt so tr?nenschwer, Keiner weiss und kennt den Tag, Jeder sehnt ihn vol Verlangen her?
(?Each one possessed it, but no one prized it. Like a cool spring it refreshed us all. What a sound the word Peace has for us now!
?Distant it sounds, and fearful, and heavy with tears. No one knows or can name the day for which all sigh with such longing.?)
***
I reflected, as doubtless many of my French readers have also done, in reading through these German writings inspired by the war ? writings through which from time to time there passes a mighty breath of revolt and sorrow ? that our young writers are not writing ?literature.? Instead of books they give us deeds, and their letters. And in re-reading some of their letters I thought that ours had chosen the better part. It is not for me now to point out the position that this heroic correspondence will occupy, not only in our history but also in our literature. Into it the flower of our youth has put all its life, its faith and its genius: and for some of those letters I would give many of the finest lines of the noblest poems. Whatever be the result of this war, and the opinion as to its value later, it will be recognized that France has written on paper, mud-stained and often blotted with blood, some of its sublimest pages. Assuredly this war touches us more nearly than it does our adversaries, for who of us would have the heart to write a play or a novel whilst his country is in danger and his brothers dying?
But I will make no comparisons between the two nations. For the present the essential thing is to show that even in Germany there are certain finer minds who are fighting against the spirit which we hate ? the spirit of grasping imperialism and inhuman pride, of military caste and the megalomania of pedants. They are but a minority ? we have no illusions about that ? and we ought to redouble our efforts on that account to vanquish the common enemy. Why then should we trouble to make these generous but feeble voices heard? Because their merit is the greater for being so little heeded; because it is the duty of those who are fighting for justice to render justice in their turn to all those men, even when they dwell in a country in which the state represents the violation of right by Faustrecht, who are defending with us the spirit of liberty.
BOSTON (AP) ? The Boston Phoenix, one of New England's oldest alternative weeklies, is shutting down after 47 years because of a long-term decline in advertising revenue.
Executive Editor Peter Kadzis said Thursday the newspaper, which covered news and the arts, has ceased print publication and is cutting 40 jobs immediately. Its last online issue will be published next week, and 10 more jobs will eventually be shed, he said.
"I cannot find the words to express how sad a moment this is for me and I know for you, as well, so I won't try," Publisher Stephen Mindich said in a memo to workers.
Mindich said sister publications in Providence, R.I., and Portland, Maine, will remain in business because their local advertising markets sustain them.
The news sparked passionate and sad reaction among fans of the Phoenix, with some paying tribute to its contribution to the discovery of great bands and music, others lamenting the loss of an independent source of news and opinions, while others remembered it as the launching pad for some national journalists.
"Heard rumor that (at)BostonPhoenix is closing!" interim U.S. Sen. Mo Cowan said on his official Twitter account. "Can't be true. Pls tell me it's not true..."
The newspaper is going out of business some six months after a reorganization that saw it absorb a smaller subsidiary publication, known as Stuff Magazine, in an effort to stem the financial loses.
"We are a text book example of sweeping market-place change," said Kadzis, who has worked at the publication for 25 years. "Our recent switch to a magazine format met with applause from readers and local advertisers. Not so, with a few exceptions, national advertisers. You can see why Warren Buffett favors small market papers over their big city brothers and sisters."
In its parting farewell, the Boston Phoenix posted to fans on its Twitter account: "Thank you Boston. Good night and good luck."
Mindich indicated in his memo that some changes would be made at the sister papers in Rhode Island and Maine.
"Because of their smaller scale of operations and because we believe that they remain meaningful publications to their communities, with some necessary changes to each, it is our intent to keep the Providence and Portland Phoenixes operating and to do so for as long as they remain financially viable," he said.
Mindich owns the Phoenix Media/Communications Group that also runs the online radio station wfnx.com, the offshoot of a station that left the FM airwaves last year. He said the alternative rock station "will not continue as it is." Officials have yet to determine the station's future.
His firm's custom publication unit and Mass Web Printing Co., which specializes in producing weekly and monthly trade and business publications for clients from its base in central Massachusetts, will remain in business.
___
Rodrique Ngowi can be reached at www.twitter.com/ngowi
VATICAN CITY (Reuters) - The monks at the convent of St. Francis in Assisi were overjoyed on Wednesday when Cardinal Jorge Bergoglio of Argentina was elected and decided to be the first pontiff in Catholic history to take the name Francis.
"For us in the Basilica in Assisi that holds the body (of St. Francis, this choice (of a name) prompted a surge of admiration ...," said Father Mauro Gambetti, the abbot of the monastery.
St. Francis still points to the path of humility and evangelical simplicity ... the path that the new pope indicated in his first words addressed to the Church," he said.
"That Church, which for St. Francis is the face of tenderness, is ready to encounter every man and recognize him as a brother. That is the face of tenderness that we saw in Pope Francis," he said.
St. Francis, who died in 1226, is associated with peace and simplicity. He relinquished his earthly goods and lived a life of poverty and simplicity.
He was the founder of the Franciscan order of priests and nuns, who run schools, hospitals and charities around the world.
(Reporting By Philip Pullella; editing by Keith Weir)
Despite many remarkable discoveries in the field of neuroscience during the past several decades, researchers have not been able to fully crack the brain's "neural code." The neural code details how the brain's roughly 100 billion neurons turn raw sensory inputs into information we can use to see, hear and feel things in our environment.
In a perspective articlepublished in the journalNature Neuroscience on Feb. 25, 2013, biomedical engineering professor Garrett Stanley detailed research progress toward "reading and writing the neural code." This encompasses the ability to observe the spiking activity of neurons in response to outside stimuli and make clear predictions about what is being seen, heard, or felt, and the ability to artificially introduce activity within the brain that enables someone to see, hear, or feel something that is not experienced naturally through sensory organs.
Stanley also described challenges that remain to read and write the neural code and asserted that the specific timing of electrical pulses is crucial to interpreting the code. He wrote the article with support from the National Science Foundation (NSF) and the National Institutes of Health (NIH). Stanley has been developing approaches to better understand and control the neural code since 1997 and has published about 40 journal articles in this area.
"Neuroscientists have made great progress toward reading the neural code since the 1990s, but the recent development of improved tools for measuring and activating neuronal circuits has finally put us in a position to start writing the neural code and controlling neuronal circuits in a physiological and meaningful way," said Stanley, a professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.
With recent reports that the Obama administration is planning a decade-long scientific effort to examine the workings of the human brain and build a comprehensive map of its activity, progress toward breaking the neural code could begin to accelerate.
The potential rewards for cracking the neural code are immense. In addition to understanding how brains generate and manage information, neuroscientists may be able to control neurons in individuals with epilepsy and Parkinson's disease or restore lost function following a brain injury. Researchers may also be able to supply artificial brain signals that provide tactile sensation to amputees wearing a prosthetic device.
Stanley's paper highlighted a major challenge neuroscientists face: selecting a viable code for conveying information through neural pathways. A longstanding debate exists in the neuroscience community over whether the neural code is a "rate code," where neurons simply spike faster than their background spiking rate when they are coding for something, or a "timing code," where the pattern of the spikes matters. Stanley expanded the debate by suggesting the neural code is a "synchrony code," where the synchronization of spiking across neurons is important.
A synchrony code argues the need for precise millisecond timing coordination across groups of neighboring neurons to truly control the circuit. When a neuron receives an incoming stimulus, an electric pulse travels the neuron's length and triggers the cell to dump neurotransmitters that can spark a new impulse in a neighboring neuron. In this way, the signal gets passed around the brain and then the body, enabling individuals to see, touch, and hear things in the environment. Depending on the signals it receives, a neuron can spike with hundreds of these impulses every second.
"Eavesdropping on neurons in the brain is like listening to a bunch of people talk?a lot of the noise is just filler, but you still have to determine what the important messages are," explained Stanley. "My perspective is that information is relevant only if it is going to propagate downstream, a process that requires the synchronization of neurons."
Neuronal synchrony is naturally modulated by the brain. In a study published in Nature Neuroscience in 2010, Stanley reported finding that a change in the degree of synchronous firing of neurons in the thalamus altered the nature of information as it traveled through the pathway and enhanced the brain's ability to discriminate between different sensations. The thalamus serves as a relay station between the outside world and the brain's cortex.
Synchrony induced through artificial stimulation poses a real challenge for creating a wide range of neural representations. Recent technological advances have provided researchers with new methods of activating and silencing neurons via artificial means. Electrical microstimulation had been used for decades to activate neurons, but the technique activated a large volume of neurons at a time and could not be used to silence them or separately activate excitatory and inhibitory neurons. Stanley compared the technique with driving a car that has the gas and brake pedals welded together.
New research methods, such as optogenetics, enable activation and silencing of neurons in close proximity and provide control unavailable with electrical microstimulation. Through genetic expression or viral transfection, different cell types can be targeted to express specific proteins that can be activated with light.
"Moving forward, new technologies need to be used to stimulate neural activity in more realistic and natural scenarios and their effects on the synchronization of neurons need to be thoroughly examined," said Stanley. "Further work also needs to be completed to determine whether synchrony is crucial in different contexts and across brain regions."
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Stanley, Garrett B., "Reading and writing the neural code," Nature Neuroscience (2013): http://dx.doi.org/10.1038/nn.3330.
Georgia Institute of Technology: http://www.gatech.edu
Thanks to Georgia Institute of Technology for this article.
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A musher travels across Norton Sound on their way to Koyuk in Alaska during the Iditarod Trail Sled Dog Race on Monday, March 11, 2013. (AP Photo/The Anchorage Daily News, Bill Roth)
A musher travels across Norton Sound on their way to Koyuk in Alaska during the Iditarod Trail Sled Dog Race on Monday, March 11, 2013. (AP Photo/The Anchorage Daily News, Bill Roth)
Aliy Zirkle puts booties on her dogs prior to leaving Koyuk on Monday, March 11, 2013, during the Iditarod Trail Sled Dog Race. (AP Photo/The Anchorage Daily News, Bill Roth)
A frost covered Sonny Lindner begins his checkpoint routine in Koyuk in Alaska during the Iditarod Trail Sled Dog Race on Monday, March 11, 2013. (AP Photo/The Anchorage Daily News, Bill Roth)
Aliy Zirkle jumps over some overflow to tend to her dog team shortly after leaving Koyuk in Alaska during the Iditarod Trail Sled Dog Race on Monday, March 11, 2013. Alaska's famous 1,000-mile Iditarod Trail Sled Dog Race has come down to a furiously contested sprint among veterans, with one seasoned musher grabbing the lead from another Monday and several others within striking distance. (AP Photo/The Anchorage Daily News, Bill Roth)
Alan Jones, an orthodontist from Huntsville, Ala., and volunteer at the Iditarod Trail Sled Dog Race, updates the musher positioning board in the Nome Convention Center on Tuesday, March 12, 2013, in Nome, Alaska. This year's winner is expected late Tuesday night in this Bering Sea coastal community. (AP Photo/Mark Thiessen)
NOME, Alaska (AP) ? Thirteen minutes.
After mushing about 930 miles across the Alaska wilderness the last nine days, that's all that separated the first two teams in the Iditarod Trail Sled Dog Race.
Mitch Seavey was the first musher into the checkpoint at White Mountain, 77 miles from the finish line in Nome. He checked in at 5:11 a.m. Tuesday, and Aliy Zirkle, last year's runner-up, followed him at 5:24 a.m.
And now it's a waiting game.
All mushers have to take an eight-hour mandatory rest at White Mountain, and then it will be a mad dash for the burled arch finish line in downtown Nome. The winner is expected sometime late Tuesday evening.
"They're both great mushers, very talented, kind of that dog whisperer that I like to call some of those top mushers," said race spokeswoman Erin McLarnon.
But at this point, it's anybody's guess who will cross the finish line first.
"Mitch doesn't have a super solid lead. I mean, 13 minutes, anything can happen," she said.
It's likely Seavey, the 2004 champion and father of last year's winner, Dallas Seavey, and Zirkle won't be alone as they make the last run on the Bering Sea coast.
Four-time champion Jeff King is in third place, and checked into White Mountain at 6:52 a.m. He and Zirkle covered the last 46-mile section of trail, from Elim to White Mountain, a half hour faster than Mitch Seavey.
Seavey and Zirkle each have 10 dogs left on their team; King arrived at White Mountain with 11.
"Last year we saw a lot of those youngsters in the top 10," McLarnon said. "Some of those 45-plussers are taking back the lead this year. They are showing the young 'uns what they can really do out there on that trail."
The defending champion and youngest winner ever, Dallas Seavey, 26, arrived in White Mountain at 8:09 and Ray Redington Jr., a grandson of a race co-founder, was two minutes behind him.
White Mountain was a crowded checkpoint Tuesday morning as other mushers arrived, including Norwegian rookie Joar Leifseth Ulsom, French native Nicolas Petit, Jake Berkowitz of Big Lake, Alaska, Nome hometown hero Aaron Burmeister and Sonny Lindner of Two Rivers, Alaska, rounding out the first ten into the checkpoint.
The excitement for a mad dash down Front Street, a block off the frozen Bering Sea, that could parallel the 1978 photo finish between winner Dick Mackey and Rick Swenson has fans gathered in Nome excited to see the end of the race.
"I think having a real race from White Mountain to Nome is probably more exciting than having the winner already decided for the most part," said Jerry Spindler II of Fort Wayne, Ind.
He previously saw the end of Iditarod in 1995 and 1999, but this trip is special since his son, Jason, is completing an internship with the race. His father, Jerry Spindler, also made his first trip to Alaska from Indiana.
The race for 66 mushers began with a ceremonial start in downtown Anchorage on March 2, and the competitive start was the following day in Willow, Alaska. Eight mushers have scratched. The latest scratches came Tuesday, from two Wasilla mushers.
Jason Mackey was attempting to become an Iditarod champion like his father, Dick, and brothers Rick and Lance, but had to pull out of the race in Unalakleet because of the flu.
Rudy Demonski Sr. also scratched in Unalakleet over concern for his dog team.
Chrome, Firefox, and Safari: Add to Wunderlist is a browser extension that submits web pages as tasks to any list in Wunderlist. You can save Amazon items to a wish list, Gmail messages to a specific project, and more.
Add to Wunderlist places a little button of the same name on any supported page, allowing you to create a task directly from the browser with the URL attached. While it doesn't work with every page (we're not sure why, as clicking the icon in the toolbar ought to have the same function), the extension currently supports Amazon, Asos, Ebay, Etsy, Hacker News, Twitter, Wikipedia, Youtube, Gmail, Yahoo! Mail, and Outlook. This is a pretty good start, but hopefully we'll see more integrations in the coming weeks as Wunderlist provides an SDK for easy integration.
Add to Wunderlist for Chrome, Firefox, and Safari (Free)
More than a year after the Costa Concordia ran aground off the Italian coast, the ship remains where it wrecked. More than 400 workers are attempting one of the largest salvage operations in history, a process that will cost around $400 million and will take at least until this summer to complete. They have a tough slog ahead: Just removing the 2100 tons of fuel took 31 days and 20 vessels. Because the ruined ship is lying on its side, the engineering teams have to hoist it upright?preserving a seabed lush with coral, sea-grass meadows, and giant clams?before towing it to a safe harbor for disassembly.
Mar. 11, 2013 ? Long-term droughts in the Southwestern North America often mean failure of both summer and winter rains, according to new tree-ring research from a University of Arizona-led team.
The finding contradicts the commonly held belief that a dry winter rainy season is generally followed by a wet monsoon season, and vice versa.
The new research shows that for the severe, multi-decadal droughts that occurred from 1539 to 2008, generally both winter and summer rains were sparse year after year.
"One of the big questions in drought studies is what prompts droughts to go on and on," said lead author Daniel Griffin, a doctoral candidate in the UA School of Geography and Development. "This gives us some indication that the monsoon and its failure is involved in drought persistence in the Southwest."
The new 470-year-long history of summer precipitation in the Southwest covers most of Arizona, western New Mexico and parts of northern Mexico.
"This is the first time researchers have used tree rings to take a closer look at the monsoon in a large and important area of the American Southwest," said Griffin, who also is an EPA STAR Research Fellow at the UA Laboratory of Tree-Ring Research.
"Monsoon droughts of the past were more severe and persistent than any of the last 100 years," he said. "These major monsoon droughts coincided with decadal winter droughts."
Those droughts had major environmental and social effects, Griffin said, pointing out that the late-16th-century megadrought caused landscape-scale vegetation changes, a 17th-century drought has been implicated in the Pueblo Revolt of 1680 and the 1882-1905 drought killed more than 50 percent of Arizona's cattle.
Co-author Connie A. Woodhouse, UA associate head and associate professor of geography and development, said, "The thing that's interesting about these droughts is that we've reconstructed the winter precipitation, but we've never known what the summers were like."
Because winter precipitation has the strongest influence on annual tree growth, previous large-scale, long-term tree-ring reconstructions of the region's precipitation history had focused only on the winter rainy season.
"Now we see -- wow -- the summers were dry, too," she said. "That has a big impact."
The team's research report, "North American monsoon precipitation reconstructed from tree-ring latewood," is scheduled for publication March 11 in Geophysical Research Letters, a journal of the American Geophysical Union.
Additional UA co-authors are David M. Meko, Holly L. Faulstich, Carlos Carrillo, Ramzi Touchan, Christopher L. Castro and Steven W. Leavitt. Co-author David W. Stahle is from the University of Arkansas in Fayetteville.
The National Science Foundation, the National Oceanic and Atmospheric Administration and the U.S. Environmental Protection Agency supported the research.
"In the Southwest, the winter precipitation is really important for water supply. This is the water that replenishes reservoirs and soil moisture," Woodhouse said. "But the monsoon mediates the demand for water in the summer."
Until recently, most tree-ring researchers, known as dendrochronologists, have looked at the total width of trees' annual rings to reconstruct past climate. Few teased out the seasonal climate signal recorded in the narrow part of the growth ring laid down in late summer known as latewood.
To figure out the region's past history of monsoon precipitation, the scientists needed to measure latewood from tree-ring samples stored in the archives of the UA Laboratory of Tree-Ring Research and go into the field to take additional samples of tree rings.
The team looked at annual growth rings from two different species, Douglas-fir (Pseudotsuga menziesii) and ponderosa pine (Pinus ponderosa) throughout the weather forecast region called North American Monsoon Region 2, or NAM2.
In all, the researchers used samples from 50 to 100 trees at each of 53 different sites throughout southwestern North America. The team's climate analyses focused on NAM2, which covers most of Arizona, western New Mexico and northern parts of the Mexican states of Sonora and Chihuahua.
Griffin said, "It was a massive undertaking -- we employed about 15 undergraduates over a four-year period to measure almost 1 million tree rings."
The results surprised him because rain gauge records for the Southwest from 1950-2000 show dry seasons alternated with wet ones.
However, the team's new multi-century record going back to 1539 shows that the wet/dry pattern of the latter part of the 20th century is not the norm -- either prior to the 20th century or now, he said.
One possible next step, Woodhouse said, is to expand the current project to other areas of the Southwest and into Mexico, where the monsoon has a bigger influence on annual precipitation.
Another would be using tree-ring reconstructions of the Southwest's fire histories to see how wildfires are related to summer precipitation.
Griffin said, "Before I moved to the Southwest, I didn't realize how critically important the summer rains are to the ecosystems here. The summer monsoon rains have allowed humans to survive in the Southwest for at least 4,000 years."
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The above story is reprinted from materials provided by University of Arizona. The original article was written by Mari N. Jensen.
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Journal Reference:
Daniel Griffin, Connie A. Woodhouse, David M. Meko, David W. Stahle, Holly L. Faulstich, Carlos Carrillo, Ramzi Touchan, Christopher L. Castro, Steven W. Leavitt. North American monsoon precipitation reconstructed from tree-ring latewood. Geophysical Research Letters, 2013; DOI: 10.1002/grl.50184
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President Barack Obama walks with Chief of Staff Denis McDonough, right, as they leave the Gridiron Dinner through a loading area at a hotel in Washington, Saturday, March 9, 2013. (AP Photo/Charles Dharapak)
President Barack Obama walks with Chief of Staff Denis McDonough, right, as they leave the Gridiron Dinner through a loading area at a hotel in Washington, Saturday, March 9, 2013. (AP Photo/Charles Dharapak)
WASHINGTON (AP) ? President Barack Obama blamed the budget battle if his jokes fell flat at Saturday night's Gridiron dinner: "My joke writers have been placed on furlough."
Always a target for digs, the president tossed out a few of his own during the Gridiron Club and Foundation dinner, an annual event where political leaders, journalists and media executives poke fun at each other.
The so-called sequester that struck the federal budget this month drew another observation from Obama: "Of course, there's one thing in Washington that didn't get cut ? the length of this dinner. Yet more proof that the sequester makes no sense."
The ambitions of 70-year-old Vice President Joe Biden? "Just the other day, I had to take Joe aside and say, 'Joe, you are way too young to be the pope. You can't do it. You got to mature a little bit.'"
During a pause in his remarks, Obama took a long, slow sip of water and then said, "That, Marco Rubio, is how you take a sip of water." Rubio took a much-discussed water break while delivering the televised GOP response to the State of the Union address last month.
Obama also mocked the criticism from some quarters that he takes time off from his job. "We face major challenges. March in particular is going to be full of tough decisions. But I want to assure you, I have my top advisers working around the clock. After all, my March Madness bracket isn't going to fill itself out. And don't worry ? there is an entire team in the Situation Room as we speak, planning my next golf outing, right now at this moment."
The dinner was the organization's 128th since its founding in 1885. Minnesota Sen. Amy Klobuchar represented the Democrats, while Louisiana Gov. Bobby Jindal cracked wise for the Republicans.
Klobuchar joked that Obama had aged in office. "His Secret Service name used to be 'Renegade,'" she said. "Now it's '50 Shades of Gray.'"
Jindal jabbed at Republican presidential nominee Mitt Romney, telling the audience that Romney had warned him that "47 percent of you can't take a joke." Referring to his own prospects for a presidential run, Jindal asked, "What chance does a skinny guy with a dark complexion have of being elected president?"
Political disputes and feuds between politicians and the news media provided plenty of fodder. There was Obama's sometimes frosty relationship with the news media, the internal struggles roiling the Republican Party, and journalist Bob Woodward's dustup with White House economic adviser Gene Sperling, who advised Woodward in an email that the veteran Watergate reporter would regret his reporting about the forced spending cuts called a sequester.
Welcoming the 650 attendees, Gridiron President Charles J. Lewis of Hearst Newspapers noted that the organization had promised to keep the evening short, "especially because Gene Sperling said that a late night is something we'd all regret."
With a nod to print reporters' complaints about dealing with the Obama administration, Lewis said he thought he'd overhead Obama say on the way to the dinner: "So many newspaper reporters. So many interviews to turn down."
Musical skits are a tradition at the Gridiron dinner. Using the Beatles song "When I'm 64," one skit featured a look at Hillary Rodham Clinton's future with the lyrics:
"Got a bit older/Growing my hair/Gained a pound or two
"Going home to vegetate in Chappaqua/ I just want to be a grandma
"It was more than a case of Benghazi flu/Still I'll be just fine
"Will you select me/Will you elect me/When I'm 69."
Noting the close relationship between the GOP and the National Rifle Association, Gridiron members sang a tune called "My Gun," a takeoff on the Temptations' "My Girl." The lyrics included:
"If you hate the NRA/Tell my Walther PPK
"You're flirting with disaster/With my Bushmaster
"And when pigs fly away/You can take me away
"From my gun."
The Gridiron Club and Foundation contributes to college scholarships and journalistic organizations. It limits active members to 65 journalists based in Washington.
Except for Grover Cleveland, every president since the Gridiron was founded has addressed it. The club is the oldest and most exclusive for Washington journalists. Its motto is, "Singe but never burn."